研究業績

2018年

宮部斉重 (主要業績)

• "Directed evolution of proteins with exceptional binding promiscuity and superior therapeutic efficacy. "
  Angelini A, Miyabe Y, Newsted D, Kwan HB, Miyabe C, Kelly RL, Jamy NM, Luster AD, Wittrup DK.
  Nature Communications 9, 1, 1461 (2018).

  • DOI: 10.1038/s41467-018-03687-x
• "CXCL10 stabilizes T cell-brain endothelial cell adhesion leading to the induction of cerebral malaria"
  Sorensen EW, Lian J, Ozga AJ, Miyabe Y, Ji SW, Bromley SK, Mempel TR, Luster AD.
  JCI Insight 3, 8, e98911 (2018).

  • DOI: 10.1172/jci.insight.98911
• "The critical role of C5a as an initiator of neutrophil-mediated autoimmune inflammation of the joint and skin"
  Sadik CD, Miyabe Y, Sezin T, Luster AD.
  Seminars in Immunology 37, 21-29 (2018).

  • DOI: 10.1016/j.smim.2018.03.002

自己免疫疾患グループ

• "Propionate-producing bacteria in the intestine may associate with skewed responses of IL10-producing regulatory T cells in patients with relapsing polychondritis."
  Shimizu J, Kubota T, Takada E, Takai K, Fujiwara N, Arimitsu N, Murayama MA, Ueda Y, Wakisaka S, Suzuki T, Suzuki N.
  PLOS One 13, e0203657 (2018).
• "Relapsing polychondritis patients were divided into three subgroups: patients with respiratory involvement (R subgroup), patients with auricular involvement (A subgroup), and overlapping patients with both involvements (O subgroup), and each group had distinctive clinical characteristics."
  Shimizu J, Yamano Y, Kawahata K, Suzuki N.
  Medicine (Baltimore) 97, 42, e12837 (2018).