研究業績

再生医療グループ

2021年

• "Defective Reelin/Dab1 signaling pathways associated with disturbed hippocampus development of homozygous yotari mice. "
  Arimitsu N, Mizukami Y, Shimizu J, Takai K, Suzuki T, Suzuki N.
  Molecular and Cellular Neuroscience 112, 103614 (2021).
• "Female dominance of both spatial cognitive dysfunction and neuropsychiatric symptoms in a mouse model of Alzheimer's disease."
  Murayama MA, Arimitsu N, Shimizu J, Fujiwara N, Takai K, Okada Y, Hirotsu C, Takada E, Suzuki T, Suzuki N.
  Exp. Anim. 70, 3, 398-405 (2021).
• "Dementia model mice exhibited improvements of neuropsychiatric symptoms as well as cognitive dysfunctions with neural cell transplantation."
  Murayama MA, Arimitsu N, Shimizu J, Fujiwara N, Takai K, Okada Y, Hirotsu C, Takada E, Suzuki T, Suzuki N.
  Exp. Anim. 70, 3, 387-397 (2021).

2019年

• "Transplantation of Human iPS Cell-Derived Neural Cells with an Artificial Nerve Conduit Leads to Cellular Retention in the Transplanted Area and Improves Motor Function in a Mouse Spinal Cord Injury Model."
  Tomochika K, Arimitsu N, Murayama MA, Hirotsu C, Nagata K, Takai K, Shimizu J, Akazawa T, Torii Y, Umehara T, Iinuma M, Niki H, Suzuki N.
  St. Marianna Med. J. 10, 27-37 (2019).
• "Roles of Reelin/Disabled1 pathway on functional recovery of hemiplegic mice after neural cell transplantation; Reelin promotes migration toward motor cortex and maturation to motoneurons of neural grafts. "
  Arimitsu N, Takai K, Fujiwara N, Shimizu J, Ueda Y, Wakisaka S, Hirotsu C, Murayama MA, Suzuki T, Suzuki N.
  Exp Neurol. 320, 112970 (2019).

2017年

• "Neuronal cell sheet of cortical motor neuron phenotype derived from human iPS cells."
  Suzuki N, Arimitsu N, Shimizu J, Takai K, Hirotsu C, Takada E, Ueda Y, Wakisaka S, Fujiwara N, Suzuki T.
  Cell Transplant. 26, 1355-1364 (2017).

2016年

• "Cellular transplantation as the treatment of Alzheimer's disease in mouse models. "
  Suzuki N, Shimizu J, Fujiwara N, Arimitsu N.
  J Alzheimers Dis Parkinsonism. 6, 219 (2016).
• "Human iPS cell derived neural cell sheets exhibit mature neural and extendable scaffold functions and promote recovery in injured mouse spinal cords."
  Arimitsu N, Shimizu J, Iinuma M, Umehara T, Fujiwara N, Takai K, Wakisaka S, Hirotsu C, Suzuki T, Beppu M, Niki H, Suzuki N.
  J Stem Cell Res Med. 1, 41-47 (2016).

2015年

• "Generation of retinal progenitor cell sheets which differentiate into rhodopsin positive photoreceptors from mouse iPS cell derived retinal progenitor cell clones."
  Suzuki N, Shimizu J, Hirotsu C, Takada E, Arimitsu N, Ueda Y, Fujiwara N, Suzuki T Takai K.
  Int J Ophthalmol Clin Res. 2, 1 (2015).
• "Induction of neural cells with spinal motoneuron phenotype from human iPS cells and the transplantation to totally transected spinal cords in mice. "
  Iinuma M, Umehara T, Arimitsu N, Shimizu J, Misawa H, Takai K, Fujiwara N, Fujii A, Ueda Y, Wakisaka S, Suzuki T, Hirotsu C, Beppu M, Suzuki N.
  Inflamm Regen. 35, 154-163 (2015).