研究業績

自己免疫疾患グループ

2023年

• "Innate immune responses in Behçet disease and relapsing polychondritis."
  Shimizu J, Murayama MA, Mizukami Y, Arimitsu N, Takai K, Miyabe Y.
  Frontiers in Medicine 10, 1055753 (2023).

  • DOI: 10.3389/fmed.2023.1055753
• "Chemokines and chemokine receptors as promising targets in rheumatoid arthritis"
  Murayama MA, Shimizu J, Miyabe C, Yudo K, Miyabe Y.
  Frontiers in Immunology 14, 1100869 (2023).

  • DOI: 10.3389/fimmu.2023.1100869

2022年

• "Immunopathology of Behcet’s disease: an overview of the metagenomic approaches"
  Jun Shimizu, Masanori A Murayama, Yoshishige Miyabe, Noboru Suzuki
  Rheumato 2, 74-86 (2022).

  • DOI: https://doi.org/10.3390/rheumato2030010
• "Mechanical model of steady-state and inflammatory conditions in patients with relapsing polychondritis: A review. "
  Shimizu J, Suzuki N.
  Medicine (Baltimore). 101, 8, e28852 (2022).
• "Nationwide cross-sectional survey of patients with relapsing polychondritis in 2019 demonstrates reduction of airway involvement compared with that in 2009. "
  Shimizu J, Yamano Y, Kawahata K, Suzuki N.
  Scientific Reports 12, 1, 465 (2022).

2021年

• "Serum MMP3 correlated with IL1β messenger RNA expressions of peripheral blood mononuclear cells in patients with relapsing polychondritis with respiratory involvement."
  Shimizu J, Wakisaka S, Suzuki T, Suzuki N.
  ACR open rheumatology 3, 636-641 (2021).

2020年

• "Elucidation of predictors of disease progression in patients with relapsing polychondritis at the onset: potential impact on patient monitoring. "
  Shimizu J, Yamano Y, Kawahata K, Suzuki N.
  BMC Rheumatology 4, 41 (2020).

2019年

• "Relative abundance of Megamonas hypermegale and Butyrivibrio species decreased in the intestine and its possible association with the T cell aberration by metabolite alteration in patients with Behcet's disease."
  Shimizu J, Kubota T, Takada E, Takai K, Fujiwara N, Arimitsu N, Ueda Y, Wakisaka S, Suzuki T, Suzuki N.
  Clinical Rheumatology 38, 1437-45 (2019).

2018年

• "Propionate-producing bacteria in the intestine may associate with skewed responses of IL10-producing regulatory T cells in patients with relapsing polychondritis."
  Shimizu J, Kubota T, Takada E, Takai K, Fujiwara N, Arimitsu N, Murayama MA, Ueda Y, Wakisaka S, Suzuki T, Suzuki N.
  PLOS One 13, e0203657 (2018).
• "Relapsing polychondritis patients were divided into three subgroups: patients with respiratory involvement (R subgroup), patients with auricular involvement (A subgroup), and overlapping patients with both involvements (O subgroup), and each group had distinctive clinical characteristics."
  Shimizu J, Yamano Y, Kawahata K, Suzuki N.
  Medicine (Baltimore) 97, 42, e12837 (2018).

2016年

• "Possible association of proinflammatory cytokines including IL1β and TNFα with enhanced Th17 cell differentiation in patients with Behcet's disease."
  Shimizu J, Takai K, Takada E, Fujiwara N, Arimitsu N, Ueda Y, Wakisaka S, Suzuki T, Suzuki N.
  Clinical Rheumatology 35, 1857-63 (2016).
• "Bifidobacteria abundance-featured gut microbiota compositional change in patients with Behcet's disease."
  Shimizu J, Takai K, Takada E, Fujiwara N, Arimitsu N, Ueda Y, Wakisaka S, Suzuki T, Suzuki N.
  PLOS One 11, e0153746 (2016).

2013年

• "Skewed helper T-cell responses to IL-12 family cytokines produced by antigen-presenting cells and the genetic background in Behcet's disease. "
  Shimizu J, Kaneko F, Suzuki N.
  Genetic Research International 2013, 2013, 363859 (2013).